Panama City 4-star Hotels

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Popular 4-star hotels in Panama City

These hotels are some of our user’s favourites in Panama City based on booking data. Prices were last updated on 2 February 2026.
Enter your travel dates to find the best prices.
56 y 57 East Street, Obarrio, Panama City, Panama
A vibrant and energetic environment in downtown Panama City, Panama for Panamanians and global travelers who crave the exceptional in every corner of life. At Sortis Hotel, Spa & Casino you are in charge and you decide your own rhythm. Your own heartbeat. Here, everything has been crafted with the guest experience in mind — from 391 high-design rooms, suites and apartments to a striking, ultramodern style that infuses every moment of the guest experience. Restaurants include Manabí, a rustic, contemporary restaurant showcasing modern Panamanian cuisine. Score, a globally inspired Sports Bar and Lounge. The pool scene, overlooking stunning city and skyline views, goes seamlessly from day to night. In addition to a family friendly kids pool and arcade, it also includes Acua, a poolside Bar and Lounge.
Free Wi-Fi
8.5
Excellent
796 reviews
Location
0.6 km from city centre
₹ 10,689
Avenida Balboa, Panama City, Panama
Let yourself be carried away by an unparalleled experience at the facilities of the most incredible hotel in Latin America and discover a luxury service inspired to make you feel like a true star. Strategically located in a central point of the great city of Panama, with immediate access to Megapolis Outlets Mall, casino, and the Megapolis Convention Center. Just 20 minutes away from the Tocumen International Airport, 8 minutes from the Old Town and 5 minutes from the City's Financial District.Characterized by imposing architecture, stunning views, infinity pool, the best entertainment, and luxury restaurants framed in an exclusive gastronomic offer for your palate, Megapolis Hotel Panama is your ideal destination.
Free Wi-Fi
Parking
8.5
Excellent
2950 reviews
Location
1.1 km from city centre
₹ 10,501
Vía Tocumen Tocumen 0819-09190 PA, Panama City, Panama
Relax your senses and enjoy the freshness of the Riande Aeropuerto Hotel & Casino, modern, comfortable and elegant, designed for a perfect stay near the Tocumen International Airport, with an ideal location for travelers.
Free Wi-Fi
Parking
8.1
Excellent
5262 reviews
Location
16.5 km from city centre
₹ 7,715
581 Calle Gaspar Hernandez Y Via Argent, Corregimiento El Cangrejo - Sector Bellavista, Panama City, PA, Panama City, Panama
Best Western Plus Panama Zen is strategically located in one of the best areas of Panama City, close to the financial and business district, shopping malls, restaurants, bars and casinos, and is only 16 kilometers from Tocumen International Airport. It is your ideal accommodation for wonderful days in Panama City, whether on a business or leisure trip. Enjoy our pool with a view of the city, restaurant, gym, business center, meeting rooms and more. The rooms have air conditioning, minibar (with additional charge), safe, 39-inch LCD TV with cable channels, hair dryer, coffee maker, cordless telephone, wake-up call service, clock radio and desk. Free high-speed Wi-Fi Internet access and parking. In our restaurant you can try the best of Panamanian cuisine, with delicious dishes and flavors. It will be a pleasure to welcome you to Best Western Plus Panama Zen!
Free Wi-Fi
8.6
Excellent
4409 reviews
Location
0.6 km from city centre
₹ 8,674
Plaza de la Independencia, C. 5a Este, Panama City, Panama
Located in the heart of the Casco Viejo, Central Hotel Panama is an icon of elegance, heritage, and hospitality. Originally opened in 1874 and fully restored, it is the first hotel in the city and a historic landmark that forms part of the UNESCO World Heritage Site. With 135 thoughtfully designed rooms offering comfort and sophistication, the hotel blends the classic charm of its historical legacy with all the modern amenities. Each space provides a unique experience that connects the past with the present, in one of Panamas most vibrant cultural districts.
Free Wi-Fi
8.6
Excellent
2124 reviews
Location
3.7 km from city centre
₹ 16,033
Calle Ramon H Jurado Edifico P, Panama City, Panama
Residence Inn Panama City is an extended-stay hotel that helps you feel connected while away from home, with spacious rooms featuring fully equipped kitchens. Our Panama City, Panama hotel is located in an exclusive area inside the Pacific Center complex, which includes a mall, hospital, theater, and cinema. If you're looking for a hotel near Pacific Center Mall, we're just steps from Multiplaza Mall and walking distance to Balboa Avenue and Cinta Costera. With easy access to South Corridor, Costa del Este is a short drive away. We're also close to the Panama Canal, Smithsonian Marine Exhibition Center, and Biomuseo. Whether you're relocating or vacationing, our hotel in downtown Panama City, Panama offer homelike surroundings, pet-friendly lodging, and thoughtful amenities to help you balance life and work.
Free Wi-Fi
Parking
8.9
Excellent
281 reviews
Location
1.7 km from city centre
₹ 14,017
Via Israel y Calle 71, San Francisco, Panama City, Panama
Welcome to the Ramada Plaza Panama Punta Pacifica, a refreshing getaway spot less than 20 kilometers from Tocumen International Airport! This full-service lodging in Panama is close to the exclusive Multiplaza mall, historic Old Panama, and the ATLAPA Convention Center. Onsite, partake in full leisure amenities and services such as - spa with facial and massage services, panoramic fitness center, outdoor pool, bar and restaurant. Take advantage of complimentary Valet Parking, as well as a business center and meeting rooms. Enjoy complimentary breakfast daily, and complimentary High Speed Internet access in rooms and public spaces. Our comfortable guest rooms feature, a business desk, safebox, mini fridge, coffeemaker, iPod docking station and HDTV. Book an affordable hotel room online today. Service animals are welcome at this hotel. All property is smoke free.
Free Wi-Fi
Parking
9.1
Excellent
3270 reviews
Location
2.0 km from city centre
₹ 7,879
Ave Eusebio Morales Esquina, Panama City, Panama
Luxury hotel with a fitness center and a 24-hour front desk An outdoor pool, a restaurant, and a fitness center are available at this smoke-free hotel. Free WiFi in public areas and free self parking are also provided. Other amenities include a bar/lounge, a coffee shop/cafe, and 24-hour room service. Gran Evenia Panama offers 100 air-conditioned accommodations with safes and hair dryers. Smart televisions come with cable channels. Bathrooms include showers with rainfall showerheads, and complimentary toiletries. This Panama City hotel provides complimentary wireless Internet access. Housekeeping is provided daily. Recreational amenities at the hotel include an outdoor pool and a fitness center.
Free Wi-Fi
Parking
8.6
Excellent
786 reviews
Location
0.3 km from city centre
₹ 11,818
Miramar Plaza, Balboa Avenue, P.O. Box 7336, Panama City, Panama
The InterContinental Miramar Hotel is an luxury hotel overlooking the Pacific Ocean and the bay of Panama. Our iconic hotel is walking distance to Panama's financial centre and close to the shopping district. Each of our elegantly appointed, spacious suites has breathtaking ocean views ideally situated to watch ships and vessels enter the world-famous Panama Canal. Relax by the pool, indulge with a spa treatment, and enjoy exquisite dining and stunning views at our Bay View Restaurant.
Free Wi-Fi
8.2
Excellent
1024 reviews
Location
1.0 km from city centre
₹ 15,984
Corregimiento de Cristobal, IA 5, Panama City, Panama
Tucked deep in the mystical Soberania National Park at the meeting place of the Chagres River and the Panama Canal, Gamboa Rainforest Reserve is an exceptional destination. Its where contemporary comfort and warm, facinating adventures come together to offer the best accommodation for experiencing the unspoiled beauty of the Panamanian rainforest.Just 30 minutes from Panama City on 340 acres overlooking the Panama Canal, you can commune with nature in a pristine environment that explorers and pirates once tread. Each of our well-appointed, eco- lodge-style rooms and suites offers an authentic and relaxing escape from the bustle and distractions of everyday life.From exhilarating aerial tram rides, night safaris on the Chagres River and Panama Canal kayaking adventures to guided boat tours, fishing expeditions and much more, Gamboa Rainforest Reserve is an exotic vacation sanctuary, where individuals, groups and families enjoy memories to last a lifetime.
Free Wi-Fi
Parking
8.2
Excellent
1747 reviews
Location
23.8 km from city centre
₹ 12,826

Travel insights for hotels in Panama City

Use these up-to-date, data-driven insights about booking a hotel in Panama City including ideal times to book, pricing trends, and more.

What is the cheapest month to book a hotel in Panama City?

The cheapest month to book a hotel in Panama City is June (₹ 13,240). Conversely, the most expensive month to stay in Panama City is December (₹ 26,443).

What is the cheapest day to stay in a hotel in Panama City?

The cheapest day to stay in Panama City is Saturday (₹ 16,557). On the other hand, travelers can expect to pay the most on Wednesday, when the average nightly price is ₹ 21,476.

How much is a hotel in Panama City tonight?

Users have found prices for hotels in Panama City tonight starting as low as ₹ 1,979, rising to an average cost of ₹ 14,535, based on searches in the last 72 hours. Prices start from ₹ 4,851 for a 4-star hotel in Panama City for tonight.

How much is a Panama City hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in Panama City this weekend for as little as ₹ 2,199/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as ₹ 2,199/night. For a 4-star hotel in Panama City, the cheapest rate recently found was ₹ 5,140/night for this weekend.

How far ahead should you book a hotel in Panama City?

Save money by booking a hotel at least 55 days before your trip to Panama City. The lowest price found when booking 55 days ahead was ₹ 1,557 per night.

Top-rated 4-star Panama City hotels

View deals on 4-star hotels in Panama City that have the highest user reviews. Review data was last updated on 2 February 2026.
These are some of the highest-rated 4-star hotels in Panama City based on user reviews.
Via Israel And 77th Street, Panama City, Panama
2.7 km from city centre
Free Wi-Fi
₹ 10,627
Avg. per night

Cheapest 4-star hotels in Panama City

Discover affordable 4-star hotels in Panama City that provide a quality experience without breaking the bank. 4-star hotels in Panama City can be found for as little as ₹ 4,306 per night. Price data was last updated on 2 February 2026
These are the lowest-priced 4-star hotels our users have recently found in Panama City. Prices may vary based on dates selected and hotel location.
Calle 53 Marbella y Avenida 5a B Sur, Panama City, Panama
0.8 km from city centre
Free Wi-Fi
Parking
₹ 4,306
Avg. per night
El Cangrejo, Via Argentina, Calle Jose Fabregas Frente al Power Club y Diagonal al Restaurante 7 Mares, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
₹ 4,769
Avg. per night
Avenida 2da Sur, Obarrio, Bella Vista, Panama City, Panama
0.1 km from city centre
Free Wi-Fi
₹ 4,821
Avg. per night
Calle D Zona 9, Panama City, Panama
0.3 km from city centre
Free Wi-Fi
Parking
₹ 4,947
Avg. per night
Calle Miguel Brostella, Panama City, Panama
2.9 km from city centre
Free Wi-Fi
Parking
₹ 5,955
Avg. per night
Avenida Eloy Alfaro y Calle 11, Panama City, Panama
3.5 km from city centre
Free Wi-Fi
₹ 6,046
Avg. per night
El Cangrejo, Calle D, Bella Vista, Panama City, Panama
0.2 km from city centre
Free Wi-Fi
Parking
₹ 6,138
Avg. per night
Calle Jose I. Fabrega y Thais de Pons Panama City 581 PA, Panama City, Panama
0.8 km from city centre
Free Wi-Fi
Parking
₹ 6,139
Avg. per night
Omar Torrijos Avenue, Panama City, Panama
14.1 km from city centre
Free Wi-Fi
Parking
₹ 6,505
Avg. per night
Avenida Aquilino De La Guardia Entre Via Espana Y Calle 52, Panama City, Panama
0.3 km from city centre
Free Wi-Fi
Parking
₹ 6,596
Avg. per night
8001 Amador Ave. & Pelicano Ave. Panama City, Panama, Panama City, Panama
5.8 km from city centre
Free Wi-Fi
Parking
₹ 7,069
Avg. per night
Calle Ricardo Arango Y Calle 53e, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
₹ 7,237
Avg. per night
Avenida Balboa-Multicentro, Panama City, Panama
1.2 km from city centre
Free Wi-Fi
Parking
₹ 7,604
Avg. per night
Ave. Manuel Espinosa Batista, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
₹ 7,696
Avg. per night

Other star-rated hotels in Panama City

Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on 2 February 2026.
Not set on a 4-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Panama City based on hotel class.
5 stars
Calle Punta Colon, Punta Pacifica, Panama City, Panama
₹ 24,774
083500257 Avenida Aquilino de la Guardia (C/ Aquilino de la Guardia) Panama City, Panama, Panama City, Panama
₹ 17,787
Calle 50, Urb. Marbella, Panama City, Panama
₹ 11,454
3 stars
Italy Avenue, Punta Paitilla, Panama City, Panama
₹ 8,301
Calle 52, Panama City, Panama
₹ 7,884
Via Argentina Calle Principal, 49, Panama City, Panama
₹ 4,672
Eusebio A Morales y Calle 49 A Oest, Panama City, Panama
₹ 7,512
Calle 49 Bella Vista, Panama City, Panama
₹ 3,665

Other accommodations in Panama City

Find deals on places to stay in Panama City that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on 2 February 2026.
Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Panama City.
Calle Ramon H Jurado Edifico P, Panama City, Panama
1.7 km from city centre
Free Wi-Fi
Parking
₹ 14,017
Avg. per night
Calle Eusebio A. Morales y Calle 55, Panama City, Panama
0.4 km from city centre
Free Wi-Fi
Parking
₹ 8,641
Avg. per night
Miramar Plaza, Balboa Avenue, P.O. Box 7336, Panama City, Panama
1.0 km from city centre
Free Wi-Fi
₹ 15,984
Avg. per night
Esquina de Ave B y Calle 12, Panama City, Panama
3.6 km from city centre
Free Wi-Fi
₹ 3,791
Avg. per night
Calle Enrique Malek, Panama City, Panama
17.9 km from city centre
Free Wi-Fi
Parking
₹ 5,772
Avg. per night

Where to stay in Panama City

Explore different areas within Panama City to find the perfect location for your stay. Map data was last updated on 2 February 2026.
The map below shows all 4-star hotels in Panama City. Zoom in to find popular attractions and click on a nearby hotel for more information about the property.

Facts about 4-star hotels in Panama City

Find useful tips and insights about 4-star hotels in Panama City to help you make the most of your experience. FAQs were last updated on 2 February 2026.
  • What is the cheapest 4-star hotel in Panama City?

    Hotel Roma Plaza is the cheapest 4-star hotel in Panama City, where prices start as low as ₹ 2,474 per night.

  • What is the best 4-star hotel in Panama City?

    In Panama City, the best 4-star hotel is La Concordia - Boutique Hotel, renowned for its 9.3 user rating and an average price of ₹ 39,507 per night.

Stay elsewhere in Panama City